How Transdermal Delivery Works?

Transdermal delivery might feel like high-tech science, but the principle is surprisingly straightforward: the skin can absorb more than we think.

Each patch is carefully engineered with a multilayer structure. The adhesive holds it in place, while the active matrix contains the functional ingredients. Permeation enhancers may be used to help these actives pass through the epidermis and into deeper layers of the skin, where they enter circulation.

One of the biggest advantages of this method is bioavailability. When taken orally, many actives are broken down in the digestive system or liver before they ever reach the bloodstream — this is known as “first-pass metabolism.” Patches bypass this entirely, meaning more of the active ingredient is absorbed where it counts.

Controlled release is another critical feature. Rather than dumping all of the active at once, patches are designed to deliver consistent amounts over time, leading to steadier effects and reduced side effects.

From vitamins and minerals to botanicals and pharmaceutical-grade actives, transdermal delivery has proven to be versatile and reliable. It’s a combination of material science, pharmacology, and engineering working together to achieve precision wellness.